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Gotu Kola

Botanical Name:

Centella erecta (L. f.) Fernald 

C. asiatica auct. non (L.) Urb.

C. repanda (Pers.) Small  

Family:

Apiaceae

 

Phylogenetic Information

Phylum: Angiosperm

Class: Eudicot

Genus: Centella L. - centella

Common names:

Gotu kola, Indian pennywort, Asiatic pennywort, Ayurvedic - Mandukaparni, TCM - ji xue cao

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Botanical Information

Identification Characteristics:

Gotu kola is a perennial herb with fan-shaped green leaves and small umbel white to purplish-pink flowers.  This creeping, low-growing herb grows in damp, swampy areas. ¹ Stolons are green to pinkish-red.  At each leaf, node roots grow to create a new plant.  Gotu kola is sensitive to colder climates and should be brought indoors or heavily mulched to protect it from frosts. ²

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Seedlings

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Leaf Node Roots

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Potential look a likes and differences between them.³  

Bacopa and gotu kola are sold in Indian markets under the same vernacular name Brahmi. There are no similar botanical appearances or constituents, just name technicalities in the Indian Market. ¹ South India - Bacopa called Brahmi.  North India - gotu kola called Brahmi. ⁴

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 Bacopa Monnieri

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Bacopa

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Gotu Kola

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Kola Nut: Misconception based on similar names.  Gotu kola does not contain caffeine and is not related to kola nut.  There is no botanical likeness and these are not in the same family.¹

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Native Region: India, Sri Lanka, Madagascar, S. Africa, C., and S. America, subtropical Asia.  Most commercial material originates from India.  Finest quality from Madagascar.  Gotu kola is commonly substituted with bacapa (Bacopa monnieri) which is in the Scrophulariaceae family. ¹

Geographical Distribution: 

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Texas Local Geographical Distribution: 

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Cultivating guidelines: Gotu kola is a heat-dependent germinator.  Sow seeds in early January (Texas) in flats under T-5 fluorescent grow light in a warm room or on a heat mat set to 80° F.³

Harvesting guidelines: Fresh is best but can be harvested all year.  The best time for drying or tincturing is in summer. ² 

Nutritional Information
 
Daily intake: 6 g dried leaf, ¼ c fresh leaf ⁸

Nutrient
Rank
Per Daily Intake of 6g
*DRI⁹
Suggested Supplementation¹⁵
Zinc
High
.02mg
8-11mg
15-30mg
Thiamin
Very High
.09mg
1-1.4
10-100mg
Sodium
Very High
65mg
1.2-1.5g
Vitamin A
Very High
3843IU
700-900Ug
2500-5000IU
Silica
High
.09mg
Not Established
1-25mg
Riboflavin
High
.08mg
1.1-1.4mg
10-50mg
Niacin
High
.7mg
12-16mg
10-100mg
Manganese
Very High
.2mg
1.8-2.3mg
3-5mg
Magnesium
High
20mg
310-420mg
250-500mg
Fat
High
5.6%
Calcium
High
99mg
1000mg
600-1000mg

Folk History and Use: 

 

Historical use is mentioned in the Chinese Shennong Herbal (circa 1st-2nd century CE).  Chinese herbalist, Li Ching-Yun, regularly used Gotu kola and was believed to have lived until he was 197 years old.  The herb was therefore called “miracle elixirs of life”.   It was used as an aphrodisiac and for treating abscesses, asthma, diarrhea, epilepsy, fever, hepatitis, high blood pressure, mental fatigue, stomach ulcers, and syphilis.  

Common use today includes treatment of chronic venous insufficiency, burn wounds, stress-related duodenal ulcers, toning stomach, scleroderma, psoriatic arthritis, and scabies.

In Ayurvedic medicine, Gotu kola is used as a tonic to reduce mental fatigue and improve mental clarity.  It is also used for internal and external ulcers, blood circulation, and reducing edema.  Treatment listed in the Ayurvedic Pharmacopoeia includes inflammation, tastelessness, fever, cough, itching, skin diseases, excessive urination, dyspnea/asthma, and anemia.  Brahma Rasayana is a mixture of herbs and fruits taken with warm milk as a cerebral tonic.

TCM uses Gotu kola for treating jaundice, heat-stroke with diarrhea, urolithiasis in the kidney, bladder, or urethra, hematuria, carbuncles, boils, and traumatic injuries. 

Gotu Kola can absorb heavy metals from contaminated soils. ⁶

Energetics:  Cooling and drying⁷

Taste:  Bitter-sweet, astringent and acrid.²

Constituents:  Main chemical components are triterpenes Asiatic acid madecassic acid (triterpene ester glycosides derived from them, asiaticoside, and madecassoside), and terminolic acid.  Brahmoside, brahminoside, and hydrocotyline have also been found in Gotu kola.¹ 

Herbal Actions:  Adaptogen and cerebral tonic. ⁷ Antidepressant, anti-inflammatory, diuretic, nervine, skin tonic, vulnerary.¹⁶

Indications: 

  • UV damage - In vitro Extract 1:6 shown to stimulate collagen synthesis better than vitamin C.  Inhibitory effect related to free radical scavenging comparable to grape seed extract. ¹⁰ 

  • Builds nerve tissues - cognition, dementia, and nerve injury.¹¹ 

  • Venous insufficiency - reduces swelling and improves blood flow. May reduce leg swelling when taken before flying.¹² 

  • Inhibition of production of HSV-2 virions.¹³

  • Anti-proliferative effect on human respiratory epithelial cells.¹⁴  

  • Cold, flu, tuberculosis, shingles, UTI.  Tonsillitis, pleurisy, hepatitis, GI issues, asthma, and increased longevity.⁵

 

Preparation methods: Tea, ointment, tincture, capsules, tablets, cosmetic preparations.¹

 

Plant parts used:  Dried aerial parts collected during the flowering period.  TCM & Ayurvedic - dried whole plant used.¹

 

Dosing strategies: 

  • Infusion - 50-60g dried leaves up to 3 times daily.²

  • Infusion - 30-90g daily (higher dose for recovery from stroke or recent injury).⁴

  • TCM: 15-30g dried, 30-60g fresh¹

  • Culinary - salads, curries, rice dishes, and beverages.²

Contraindications (medications, life stages, health issues, etc.): 

 

Adverse reactions for large doses can cause irritations, drowsiness, nausea, vertigo, headaches.  Avoid if hyperthyroid.² 

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Traditional Sri Lankan Sambola²

  • 3 c Gotu kola

  • 3 tbsp fresh grated coconut

  • 1 green chili

  • ½ red onion

  • 1 tsp Maldivian fish powder (optional),

  • Juice of ½ lime

  • Salt to taste

Finely shred Gotu kola, onions, and chili.  Mix together and add lime juice. 

Citations:

  1. Engels, G. & Brinkmann, J. (2011).  Gotu kola.  HerbalGram, Volume 90 (pg 1-5).  

  2. Hilterman, K. (2018).  Gotu kola. Herb Federation of New Zealand’s Herb Awareness Week 2018.  Retrieved from: https://herbs.org.nz/gotu-kola-fact-sheet-pennywort/

  3. Carpenter, J. & Carpenter, M. (2015).  The organic medicinal herb farmer.  Chelsea Green Publishing:VT.

  4. Khalsa, K. P. (2019).  Relax:  Natural solutions for stress, anxiety, & inflammation.  Retrieved from: https://herbmentor.learningherbs.com/relax/

  5. Natural Medicines (2020).  Gotu kola.  Retrieved from:  https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=753

  6. Roslan, Rasyikin et al. (2016).  Erosion and soil contamination control using coconut flake and plantation of Centella asiatica and Chrysopogon zizanioides.  International Engineering Research and Innovation Symposium (IRIS). 
    Retrieved from:  https://iopscience.iop.org/article/10.1088/1757-899X/160/1/012082/pdf

  7. Easley, T. & Horne, S. (2016).  The modern herbal dispensatory.  North Atlantic Books: CA

  8. Pederson, M. (1998).  Nutritional herbology: A reference guide to herbs.  IN: Whitman Publications.

  9. Medeiros, D.M. & Wildman, R.E.C. (2015).  Advanced human nutrition.  MA: Jones & Bartlett Learning.

  10. Hashim, P et al. (2011).  Triterpene composition and bioactivities of Centella asiatica. Molecules (16) pg. 1310-1322.  Retrieved from:  https://www.mdpi.com/1420-3049/16/2/1310/htm

  11. Lokanathan, Y., Omar, N., Puzi, N.N.A., Saim, A. & Idrus, R. H. (2015).  Recent updates in neuroprotective and neuroregenerative potential of Centella asiatica.  Malaysian Journal of Medical Sciences. 23(1), pg 4-14. Retrieved from:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975583/pdf/2ramjms231.pdf

  12. PennStateHershey (2015).  Gotu kola.  Retrieved from:  http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000253#:~:text=Venous%20insufficiency%20and%20varicose%20veins&text=Several%20small%20studies%20suggest%20gotu,to%20those%20who%20took%20placebo

  13. Yoosook, C., Bunyapraphatsara, N. Boonyakiat, Y., & Kantasuk, C. (2000).  Anti-herpes simplex virus activities of crude water extracts of Thai medicinal plants.  Phytomedicine (6) pg 411-419.  Retrieved from:  https://www.sciencedirect.com/science/article/abs/pii/S0944711300800689?via%3Dihub

  14. Mutuna, P.M., Gicheru, M.M., Makanya, A.N., & Kiama, S.G. (2013).  Anti-proliferative activities of Centella asiatica extracts on human respiratory epithelial cells in vitro.  International Journal of Morphology, 31(4), pg 1322-1327.  Retrieved from: http://erepository.uonbi.ac.ke/bitstream/handle/11295/73697/Anti-Proliferative%20Activities%20of%20Centella%20Asiatica%20Extracts%20on.pdf?sequence=2&isAllowed=y

  15. Murray, M.T. & Pizzorno, J. (2012).  The encyclopedia of natural medicine (3rd ed).  Pg 72.  NY: Atria Paperback.

  16. Petersen, D. (2017).  Advanced herbal materia medica II (17th ed)/Herb 503.  OR: ACHS

  17. Deane (nd).  Pennyworts making sense.  Retrieved from:  http://www.eattheweeds.com/tag/centella-erecta/

  18. Cognitive Vitality (2015).  Bacopa monnieri.  Retrieved from:  https://www.alzdiscovery.org/cognitive-vitality/ratings/bacopa-monnieri

  19. Retrieved from:  https://www.chandika.com/

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